Artikler: Tidlig diagnose

Artikler iht.:

Tidlig diagnose af Tarmkræft

 

Circulating cell-free nucleosomes as biomarkers for early detection of colorectal cancer.

Rasmussen L, Christensen IJ, Herzog M, et al.

Oncotarget 2017, in press.

 

Direct detection of early-stage cancers using circulating tumor DNA.

Phallen J, Sausen M, Adleff V, Leal A, Hruban C, White J, Anagnostou V, Fiksel J, Cristiano S, Papp E, Speir S, Reinert T, Orntoft MW, Woodward BD, Murphy D, Parpart-Li S, Riley D, Nesselbush M, Sengamalay N, Georgiadis A, Li QK, Madsen MR, Mortensen FV, Huiskens J, Punt C, van Grieken N, Fijneman R, Meijer G, Husain H, Scharpf RB, Diaz LA, Jones S, Angiuoli S, Ørntoft T, Nielsen HJ, Andersen CL, Velculescu VE

Science translational medicine (2017 Aug) Issue 403 issn:1946-6242)

 

Discovery and validation of a colorectal cancer classifier in a new blood test with improved performance for high-risk subjects

Croner LJ, Dillon R, Kao A, Kairs SN, Benz R, Christensen IJ, Nielsen HJ, Blume JE, Wilcox B

Clinical proteomics (2017 ) p. 28 issn:1542-6416)

 

Detection of colorectal neoplasia: Combination of eight blood-based, cancer-associated protein biomarkers.

Wilhelmsen M, Christensen IJ, Rasmussen L, Jørgensen LN, Madsen MR, Vilandt J, Hillig T, Klaerke M, Nielsen KT, Laurberg S, Brünner N, Gawel S, Yang X, Davis G, Heijboer AM, Martens F, Nielsen HJ

International journal of cancer (2016 Dec) issn:1097-0215)

 

Protocol outlines for parts 1 and 2 of the prospective Endoscopy III study for the early detection of colorectal cancer: Validation of a concept based on blood biomarkers

Rasmussen L, Wilhelmsen M, Christensen IJ, Andersen J, Jørgensen LN, Rasmussen M, Hendel JW, Madsen MR, Vilandt J, Hillig T, Klærke M, Münster AM, Andersen LM, Andersen B, Hornung N, Erlandsen EJ, Khalid A, Nielsen HJ

JMIR research protocols (2016 ) Issue 3 p. e182 issn:1929-0748)

 

miRNA profiling of circulating EpCAM+ extracellular vesicles: Promising biomarkers of colorectal cancer

Ostenfeld MS, Jensen SG, Jeppesen DK, Christensen LL, Thorsen SB, Stenvang J, Hvam ML, Thomsen A, Mouritzen P, Rasmussen MH, Nielsen HJ, Ørntoft TF, Andersen CL

Journal of extracellular vesicles (2016 ) p. 31488

 

Increased serological cancer-associated biomarkers and risk of development of primary malignancy after large bowel endoscopy. | Colorectal Cancer Research – Forskning i tarmkræft

Nielsen, HJ

Scand J Gastroenterol. 2016 Oct;51(10):1272. doi: 10.1080/00365521.2016.1195442. Epub 2016 Jun 16.

 

Pre-analytical variables of circulating cell-free nucleosomes containing 5-methylcytosine DNA or histone modification H3K9Me3.

Rasmussen L,  Herzog M.,  Rømer E.,  Micallef J,  Bulut O.,  Wilhelmsen M.,  Christensen I., Nielsen HJ.

Scand J Clin Lab Invest. 2016 Oct;76(6):448-53. doi: 10.1080/00365513.2016.1190862. Epub 2016 Jun 13.

 

Plasma levels of OLFM4 in normals and patients with gastrointestinal cancer.

Clemmensen SN, Glenthøj AJ, Heebøll S, Nielsen HJ, Koch C, Borregaard N.

J Cell Mol Med. 2015 Dec;19(12):2865-73. doi: 10.1111/jcmm.12679. Epub 2015 Sep 28.

 

Blood-based Biomarkers at Large Bowel Endoscopy and Prediction of Future Malignancies.

Kring TS, Piper TB, Jørgensen LN, Olsen J, Rahr HB, Nielsen KT, Laurberg S, Davis G, Dowell B, Johansen JS, Christensen IJ, Brünner N, Nielsen HJ.

Biomark Cancer. 2015 Oct 22;7:57-61. doi: 10.4137/BIC.S31330. eCollection 2015.

 

Performance of the colorectal cancer screening marker Sept9 is influenced by age, diabetes and arthritis: a nested case-control study.

Ørntoft MB, Nielsen HJ, Ørntoft TF, Andersen CL; Danish Study Group on Early Detection of Colorectal Cancer.

BMC Cancer. 2015 Oct 29;15:819. doi: 10.1186/s12885-015-1832-6.

 

Plasma TIMP-1 and CEA as Markers for Detection of Primary Colorectal Cancer: A Prospective Validation Study Including Symptomatic and Non-symptomatic Individuals.

Christensen IJ, Brünner N, Dowell B, Davis G, Nielsen HJ, Newstead G, King D.

Anticancer Res. 2015 Sep;35(9):4935-41.

 

Serum YKL-40 in risk assessment for colorectal cancer: a prospective study of 4,496 subjects at risk of colorectal cancer.

Johansen JS, Christensen IJ, Jørgensen LN, Olsen J, Rahr HB, Nielsen KT, Laurberg S, Brünner N, Nielsen HJ.

Cancer Epidemiol Biomarkers Prev. 2015 Mar;24(3):621-6. doi: 10.1158/1055-9965.EPI-13-1281. Epub 2015 Jan 18.

 

Evaluation of complement proteins as screening markers for colorectal cancer.

Storm L, Christensen IJ, Jensenius JC, Nielsen HJ, Thiel S; Danish Study Group on Early Detection of Colorectal Cancer.

Cancer Immunol Immunother. 2015 Jan;64(1):41-50. doi: 10.1007/s00262-014-1615-y. Epub 2014 Sep 27.

 

Circulating intact and cleaved forms of the urokinase-type plasminogen activator receptor: biological variation, reference intervals and clinical useful cut-points.

Thurison T, Christensen IJ, Lund IK, Nielsen HJ, Høyer-Hansen G.

Clin Chim Acta. 2015 Jan 15;439:84-90. doi: 10.1016/j.cca.2014.10.004. Epub 2014 Oct 13

 

Data fusion in metabolomic cancer diagnostics

Bro R, Nielsen HJ, Savorani F, Kjeldahl K, Christensen IJ, Brünner N, Lawaetz AJ

Metabolomics : Official journal of the Metabolomic Society (2013 Feb) Issue 1 p. 3-8 issn:1573-3882)

 

Grundliggende data for “Triage i screening for tarmkræft”:

Serological biomarkers in triage of FIT-positive subjects?

Nielsen HJ, Christensen IJ, Andersen B, Rasmussen M, Friis-Hansen LJ, Bygott T, MiCallef J; Danish–Belgian Research Group on Early Detection of Colorectal Cancer.
Scand J Gastroenterol. 2017 Jun – Jul;52(6-7):742-744. doi: 10.1080/00365521.2017.1299212. Epub 2017 Mar 8.
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