Discovery and validation of a colorectal cancer classifier in a new blood test with improved performance for high-risk subjects.

Clinical proteomics (2017 )
p. 28 issn:1542-6416)

The aim was to improve upon an existing blood-based colorectal cancer (CRC) test directed to high-risk symptomatic patients, by developing a new CRC classifier to be used with a new test embodiment. The new test uses a robust assay format-electrochemiluminescence immunoassays-to quantify protein concentrations. The aim was achieved by building and validating a CRC classifier using concentration measures from a large sample set representing a true intent-to-test (ITT) symptomatic population.

Forfattere: Croner LJ, Dillon R, Kao A, Kairs SN, Benz R, Christensen IJ, Nielsen HJ, Blume JE, Wilcox B

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