Early detection of recurrence after curative resection for colorectal cancer – obstacles when using soluble biomarkers?

Scandinavian journal of gastroenterology (2013 Mar)
Issue 3 p. 326-33 issn:1502-7708)

Results from monitoring studies using biomarkers in blood samples aiming at early detection of recurrent colorectal cancer (CRC) are presently evaluated. However, some serological biomarker levels are influenced by the surgical trauma, which may complicate translation of the levels in relation to recurrence. The primary purpose of the present study was to evaluate the frequency of postoperative surgical interventions during a follow-up period of patients who have undergone surgery for primary CRC.

Forfattere: Nielsen HJ, Jess P, Aldulaymi BH, Jørgensen LN, Laurberg S, Nielsen KT, Madsen MR, Brünner N, Christensen IJ

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