Polymorphisms in the MASP1 gene are associated with serum levels of MASP-1, MASP-3, and MAp44.

PloS one (2013 )
Issue 9 p. e73317 issn:1932-6203)

MASP-1 is the first protein in the activation of the lectin pathway and MASP-1 is, like its isoforms MASP-3 and MAp44, encoded by the MASP1 gene. Our aim was to explore associations between polymorphisms in MASP1 and corresponding concentrations of MASP-1, MASP-3, and MAp44 in plasma as well as the genetic contribution to the equilibrium between the three proteins.

Forfattere: Ammitzbøll CG, Steffensen R, Jørgen Nielsen H, Thiel S, Stengaard-Pedersen K, Bøgsted M, Jensenius JC

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